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Featured Treatments

SLT (Selective Laser Trabeculoplasty) for Glaucoma

Laser surgery has become increasingly popular as an alternative method of treating pressure.


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IPL (Intense Pulsed Light) For Dry Eyes

New revolutionary device for the treatment of dry eyes due to Blepharitis/Meibomian gland dysfunction (MGD), the E-Eye IPL machine.


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Selective Laser Trabeculoplasty vs. Eye Drops

Selective Laser Trabeculoplasty vs. Eye Drops for first line treatment of Ocular Hypertension and Glaucoma: a multicentre randomised controlled trial

Gus Gazzard, Evgenia Konstantakopoulou, David Garway-Heath, Anurag Garg, Victoria Vickerstaff, Rachael Hunter, Gareth Ambler, Catey Bunce, Richard Wormald, Neil Nathwani, Keith Barton, Gary Rubin, Marta Buszewicz; on behalf of the LiGHT Trial Study Group*



Primary Open Angle Glaucoma and Ocular Hypertension are commonly treated with eye drops that lower eye pressure. SLT (Selective Laser Trabeculoplasty) is a safe alternative but is rarely used as first line treatment. This study compared the two.


In this observer masked, randomized controlled trial treatment – naïve patients with open angle glaucoma or ocular hypertension and no ocular comorbidities were recruited between 2012 and 2014 at six UK hospitals.

They were randomly allocated (web-based randomisation) to initial treatment with SLT or to eye drops as first line treatment.

An objective target Intraocular Pressure was set according to the severity of the patient’s glaucoma.

The primary outcome was health-related quality of life (HRQoL) at 3 years (assessed by EQ-5D).

Secondary outcomes were cost and cost effectiveness, disease specific HRQoL, clinical effectiveness and safety.


Of 718 patients enrolled, 356 were randomised to the selective laser Trabeculoplasty and 362 to the eye drops group.

652 (91%) returned the primary outcome questionnaire at 36 months. Average EQ-5D score was 0.86 (SD 0.18) in the Selective Laser Trabeculoplasty group versus 0.90 (SD 0.16) in the eye drops group. Therefore there was no significant difference to a patient’s quality of life.

At 36 months 74.2% of patients in the SLT group required no drops to maintain intraocular pressure at target.

Eyes of patients in the Selective Laser Trabeculoplasty group were within target intraocular pressure at more visits (93%) than in the eye drops group (91.3%).

No patients required glaucoma surgery to lower intraocular pressures in the SLT group, while 11 patients from the drops group required further surgical intervention.


Selective Laser Trabeculoplasty should be offered as first line treatment for open angle glaucoma and ocular hypertension, supporting a change in clinical practice. At the cork eye clinic SLT is now our first line treatment offered to all suitable glaucoma and ocular hypertension patients. Published online March 9, 2019



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Clinic Location 

Cork Eye Clinic

Suite 7/8, Clinic A,
Cork Clinic, Western Road,
Cork, T12 VY83.


cork eye clinic

Tel:  021 434 1030
Fax: 021 434 1033


VIEW ALLWhat Our Patients Say

Dear Mr. Golchin, Greetings from Nigeria. I hope you are well as this leaves me thank God. This is just a short note to thank you very much for the wonderful job you did on my eye on 21st July. I can now read without glasses. My long distance sight is also better. I hope all your family are keeping very well. Once again my profound gratitude for the great care you have taken of me. May God bless you, your family and your great work today and always!




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